- Ca2+ Activated K+ Channels (4)
- Ligand-Gated Ion Channels (15)
- Store-Operated Ca2+ Channels (6)
- TRP Channels (5)
Alomone Labs FITC-conjugated extracellular antibodies offer you significant advantages. Skip cell permeabilization/fixation.
NOW you can conduct flow cytometry using live cells in ONE single step.
These novel antibodies save you valuable time and resources, while empowering your research results.
✓ Developed for flow cytometry (FACS)
✓ Tested with appropriate isotype control
✓ No need for secondary antibodies
✓ Conjugated to “extracellular” antibodies
✓ Cell-surface detection of proteins
✓ Permeabilization & cell fixation not required
✓ Time saving
Within our antibody portfolio, we gladly take on special requests for customized antibody labeling/conjugation.
Ca2+ can influence various cellular outcomes by either entering the cell from the extracellular milieu or by being released from intracellular stores, such as the endoplasmic reticulum (ER). Ca2+ release from the ER is influenced by a number of factors like the activation of G-protein coupled receptors and receptor tyrosine kinases which activate downstream pathways leading to Ca2+ release. There are also membrane proteins located on the ER membrane which are known to influence Ca2+ release. Such proteins include IP3R, ryanodine receptors (RyRs) and various pumps. Many compounds can either promote or inhibit Ca2+ release from the ER. Alomone Labs is pleased to offer various small molecules and peptides known to modulate Ca2+ release from intracellular stores.