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SK (Non-BKCa) Channel Antibody Explorer Kit

A Screening Package of SK (Non-BKCa) Channel Antibodies Economically Priced
  • Lyophilized Powder
  • Antigen Incl.
Cat #: AK-218
Last update: 24/01/2020

Alomone Labs is pleased to offer the SK (Non-BKCa) Channel Antibody Explorer Kit (#AK-218). The Explorer Kit contains non-BKCa channel antibodies, ideal for screening purposes.

For research purposes only, not for human use

Compounds

Compounds
Note A mouse monoclonal antibody (#ALM-051) and guinea pig polyclonal antibody (#AGP-045) are included in this Explorer Kit. Please take into account when reacting with a secondary antibody.

Scientific Background

Scientific Background
    • Ca2+-dependent K+ (KCa) channels are divided according to biophysical properties and gene homology into two main groups. KCa were first divided according to their single channel conductance, which represents the speed by which the K+ passes via the open channel. The first group consists of small and intermediate conductance channels (SK and IK respectively, the KCNN gene family). The second group is comprised of large/big conductance channels (called BKCa or maxi K+, encoded by the slo or KCNMA1 gene)1.
      1. Coetzee, W.A. et al. (1999) Annals N.Y. Acad. Sci. 868, 233.

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