GPCR Pain-Related Antibody Explorer Kit

A Screening Package of GPCR Pain-Related Antibodies Economically Priced
  • Lyophilized Powder
  • Antigen Incl.
Cat #: AK-545
Last update: 24/01/2020

Alomone Labs is pleased to offer the GPCR Pain-Related Antibody Explorer Kit (#AK-545). The Explorer Kit contains GPCR pain-related antibodies, ideal for screening purposes.

For research purposes only, not for human use

Scientific Background

Scientific Background
    • Cannabinoids have been used in eastern medicine for many years as pain relievers.1 Δ9-tetrahydrocannabinol (THC), the major psychoactive compound in marijuana and hashish, has been shown to interact with two specific cannabinoid receptors: cannabinoid receptor 1 (CB1 Receptor or CB1R) and cannabinoid receptor 2 (CB2 Receptor or CB2R).2

      All three classic opioid receptors mediate opioid-induced analgesia. Supraspinal analgesia is mainly mediated by the µ-opioid receptor, whereas µ-, δ-, and κ-receptors participate in the control of pain at the spinal level.3

      1. Brooks, J.W. and Fraquhar-Smith, M.A. (2003) Br. J. Anaesth3, 175.
      2. Howlett, A.C. (2002) Prostaglandins Other Lipid Mediat. 68–69, 619.
      3. Matthes, H.W. et al. (1998) J. Neurosci. 18, 7285.
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