Lyophilized Powder This product is freeze dried. All water molecules have been removed.
Bioassay Tested This antibody has undergone quality control and has been approved by our professional team.
Alomone Labs is pleased to offer the TRPM8 Channel Modulator Explorer Kit (#EK-152). The Explorer Kit contains TRPM8 channel modulators, ideal for screening purposes.
| Product Name | Cat # | Size |
|---|---|---|
AMG-9090 | A-300 | 1 x 5 mg |
AMTB hydrochloride | A-305 | 1 x 5 mg |
AMG2850 | A-340 | 1 x 5 mg |
D-3263 hydrochloride | D-195 | 1 x 5 mg |
Frescolat MGA | F-165 | 1 x 1 g |
Icilin | I-145 | 1 x 5 mg |
M8-B hydrochloride | M-220 | 1 x 5 mg |
RQ 00203078 | R-170 | 1 x 5 mg |
TC-I 2014 | T-200 | 1 x 5 mg |
WS 3 | W-100 | 1 x 1 g |
WS 12 | W-105 | 1 x 5 mg |
TRPM8 channel is the cold and menthol receptor activated by either cold temperatures(~28°C) or menthol.1
TRPM8 is expressed in dorsal root ganglia (DRGs) where about 5%-10% of the small diameter DRG neurons express the channel.2,3 In DRGs, TRPM8 expressing neurons do not express the TRPV1 channel.4 Overexpression of TRPM8 was found in prostate cancer cells. However, the physiological and pathological roles that these cells play is still elusive.5 In prostate, it was suggested that TRPM8 might play a possible role in the progression of cancer to the metastatic stage.5
