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TRPM Channel Antibody Explorer Kit

A Screening Package of TRPM Channel Antibodies Economically Priced
  • Lyophilized Powder
  • Antigen Incl.
Cat #: AK-210
Sizes: 16 Vials
Last update: 23/04/2019

Alomone Labs is pleased to offer the TRPM Channel Antibody Explorer Kit (#AK-210). This Explorer Kit includes antibodies directed against TRPM channels.

For research purposes only, not for human use
Compounds
Product Name Cat # Size
Anti-Human TRPM1 Antibody
 		ACC-041 1 x 50 µl
Anti-TRPM2 Antibody
 		ACC-043 1 x 50 µl
Anti-TRPM3 (extracellular) Antibody
 		ACC-050 1 x 50 µl
Anti-TRPM4 Antibody
 		ACC-044 1 x 50 µl
Anti-TRPM5 Antibody
 		ACC-045 1 x 50 µl
Anti-TRPM6 (extracellular) Antibody
 		ACC-046 1 x 50 µl
Anti-TRPM7 Antibody
 		ACC-047 1 x 50 µl
Anti-TRPM8 (extracellular) Antibody
 		ACC-049 1 x 50 µl
Scientific Background

    • TRP channels are a large family (about 28 genes) of plasma membrane, non-selective cationic channels that are either specifically or ubiquitously expressed in excitable and non-excitable cells.1 The TRP channels have putative six-transmembrane domains (TM) with a pore domain between the fifth and the six TM, and all assemble as tetramers. Both the N- and the C-terminus of all TRPs are intracellular.3

      According to IUPHAR the TRP family comprises of three main subfamilies on the basis of sequence homology; TRPC (canonical), TRPV (vanilloid) and TRPM (melastatin). To date, three extra subfamilies are also considered to belong to the TRP family; the TRPA, TRPML, and the TRPP.1-4

      The TRPM subfamily consists of eight members, TRPM1 to TRPM8, which also can be further subdivided into four subgroups based on their sequence homology: (1)TRPM1 and TRPM3 (2) TRPM6 and TRPM7 (3) TRPM4 and TRPM5 (4) TRPM2 and TRPM8.5
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