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This product is freeze dried. All water molecules have been removed.
- Antigen Incl. Control Antigen Included
This antibody is shipped with its antigen FREE of charge!
Alomone Labs is pleased to offer the TRPM Channel Antibody Explorer Kit (#AK-210). This Explorer Kit includes antibodies directed against TRPM channels.
|Product Name||Cat #||Size|
Anti-Human TRPM1 Antibody
|ACC-041||1 x 50 µl|
|ACC-043||1 x 50 µl|
Anti-TRPM3 (extracellular) Antibody
|ACC-050||1 x 50 µl|
|ACC-044||1 x 50 µl|
|ACC-045||1 x 50 µl|
Anti-TRPM6 (extracellular) Antibody
|ACC-046||1 x 50 µl|
|ACC-047||1 x 50 µl|
Anti-TRPM8 (extracellular) Antibody
|ACC-049||1 x 50 µl|
TRP channels are a large family (about 28 genes) of plasma membrane, non-selective cationic channels that are either specifically or ubiquitously expressed in excitable and non-excitable cells.1 The TRP channels have putative six-transmembrane domains (TM) with a pore domain between the fifth and the six TM, and all assemble as tetramers. Both the N- and the C-terminus of all TRPs are intracellular.3
According to IUPHAR the TRP family comprises of three main subfamilies on the basis of sequence homology; TRPC (canonical), TRPV (vanilloid) and TRPM (melastatin). To date, three extra subfamilies are also considered to belong to the TRP family; the TRPA, TRPML, and the TRPP.1-4
The TRPM subfamily consists of eight members, TRPM1 to TRPM8, which also can be further subdivided into four subgroups based on their sequence homology: (1)TRPM1 and TRPM3 (2) TRPM6 and TRPM7 (3) TRPM4 and TRPM5 (4) TRPM2 and TRPM8.5