TRPM8 Channel Activator Explorer Kit

A Screening Package of TRPM8 Channel Activators Economically Priced
  • Lyophilized Powder
  • Bioassay Tested
Cat #: EK-150
Sizes: 5 Vials
Last update: 24/04/2019

Alomone Labs is pleased to offer the TRPM8 Channel Activator Explorer Kit (#EK-150). The Explorer Kit contains TRPM8 channel activators, ideal for screening purposes.

For research purposes only, not for human use
Product NameCat #Size
D-3263 hydrochloride
D-195 1 x 5 mg
Frescolat MGA
F-165 1 x 1 g
I-145 1 x 5 mg
WS 3
W-100 1 x 1 g
WS 12
W-105 1 x 5 mg
    • TRPM8 channel is the cold and menthol receptor activated by either cold temperatures(~28°C) or menthol.1

      TRPM8 is expressed in dorsal root ganglia (DRGs) where about 5%-10% of the small diameter DRG neurons express the channel.2,3 In DRGs, TRPM8 expressing neurons do not express the TRPV1 channel.Overexpression of TRPM8 was found in prostate cancer cells. However, the physiological and pathological roles that these cells play is still elusive.5 In prostate, it was suggested that TRPM8 might play a possible role in the progression of cancer to the metastatic stage.5

      1. Dragoni, I. et al. (2006) J. Biol. Chem. 281, 37353.
      2. Zhang, L. et al. (2006) Endocr. Relat. Cancer 13, 27.
      3. Brauchi, S. et al. (2004) Proc. Natl. Acad. Sci. 101, 15494.
      4. McKemy, D.D. et al. (2002) Nature 416, 52.
      5. Peier, A.M. et al. (2002) Cell 108, 705.
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