Alomone Labs has developed two innovative platforms for studying protein-protein interaction and/or protein co-localization in complex immunostaining or immunoprecipitation protocols:
ATTO-Conjugated Antibodies: These antibodies can be used in immunohistochemistry (IHC) and immunocytochemistry (ICC) with same species antibodies.
Save time and resources with ONE antibody.
Benefits of immunostaining with ATTO-conjugated antibodies:
✓ Direct immuno-fluorescence
✓ Secondary antibodies are not necessary
✓ Ideal for immuno-colocalization with same species/host antibodies
Guinea Pig-Raised Antibodies: Antibodies raised in guinea pig can be used with any non-guinea pig second species antibodies (e.g. antibodies raised in mouse, rabbit, goat, etc.) in complex immunostaining or immunoprecipitation protocols. Our line of guinea pig raised antibodies can be combined with any of our rabbit-raised or ATTO-conjugated antibodies in complex immunostaining protocols.
Hyperpolarization-activated and cyclic nucleotide-gated (HCN) channels comprise a small subfamily of proteins within the superfamily of pore-loop cation channels. In mammals, the HCN channel family comprises four members (HCN1-4) that are expressed in the heart and in the nervous system. Hyperpolarization-activated cation currents produced by HCN channels (Ih, If or Iq), contribute to a wide range of physiological functions including cardiac and neuronal pacemaker activity, the setting of resting potentials, dendritic integration of synaptic transmission and learning.