Overview
Cat #: EK-110
Size: 21 Vials
Form: Lyophilized
Alomone Labs is pleased to offer the CaV2 Channel Blocker Explorer Kit (#EK-110). The Explorer Kit contains many classical CaV2 channel blockers, ideal for screening purposes.
For research purposes only, not for human use
Compounds
| Product Name | Cat # | Size |
|---|---|---|
α-Conotoxin PeIA |
STC-970 | 1 x 0.1 mg |
ω-Agatoxin IVA |
STA-500 | 1 x 0.1 mg |
ω-Agatoxin TK |
STA-530 | 1 x 50 µg |
ω-Conotoxin CnVIIA |
STC-800 | 1 x 0.1 mg |
ω-Conotoxin CVIA |
STC-750 | 1 x 50 µg |
ω-Conotoxin CVIB |
STC-410 | 1 x 50 µg |
ω-Conotoxin CVIC |
STC-420 | 1 x 50 µg |
ω-Conotoxin CVIE |
STC-760 | 1 x 50 µg |
ω-Conotoxin GVIA |
C-300 | 1 x 0.1 mg |
ω-Conotoxin MVIIA |
C-670 | 1 x 0.1 mg |
ω-Conotoxin MVIIC |
C-150 | 1 x 0.1 mg |
ω-Conotoxin MVIID |
STC-751 | 1 x 50 µg |
ω-Conotoxin RVIA |
STC-850 | 1 x 0.1 mg |
ω-Conotoxin SO3 |
STC-470 | 1 x 0.1 mg |
ω-Grammotoxin SIA |
G-450 | 1 x 5 µg |
Cilnidipine |
C-135 | 1 x 5 mg |
FTX-3.3 |
F-120 | 1 x 1 mg |
sFTX-3.3 |
F-130 | 1 x 1 mg |
Huwentoxin-I |
STH-050 | 1 x 0.1 mg |
PD 173212 |
P-105 | 1 x 5 mg |
SNX-482 |
RTS-500 | 1 x 50 µg |
Scientific Background
Scientific Background
Voltage-dependent Ca2+ channels (CaV) form an important route for Ca2+ entry into cells upon deviations from the cell's resting membrane potential. There are ten CaV α1 subunit genes, divided into three subfamilies on both a functional and sequence homology basis. The CaV1 subfamily includes four genes which encode the L-type channels, the CaV3 subfamily includes three genes encoding the T-type channels and the CaV2 subfamily consists of three isoforms encoding P/Q- , N- and R-type channels, with all three contributing to neurotransmitter release in neurons.
References
- Catterall, W.A. et al. (2003) Pharmacol. Rev. 55, 579.
