Angiotensin II Receptor Antagonist Explorer Kit

A Screening Package of Angiotensin II Receptor Antagonists Economically Priced
  • Lyophilized Powder
  • Bioassay Tested
Cat #: EK-370
Last update: 24/01/2020

Alomone Labs is pleased to offer the Angiotensin II Receptor Antagonist Explorer Kit (#EK-370). The Explorer Kit contains angiotensin II receptor antagonists, ideal for screening purposes.

For research purposes only, not for human use


Product NameCat #Size
A-245 1 x 10 mg
C-266 1 x 50 mg
EMD 66684
E-160 1 x 5 mg
Eprosartan mesylate
E-145 1 x 50 mg
Losartan potassium
L-185 1 x 500 mg
O-125 1 x 100 mg
T-170 1 x 50 mg
V-120 1 x 50 mg

Scientific Background

    • Ang II is the peptide hormone that generates most of the known effects of the renin-angiotensin system (RAS). Ang II is generated from the angiotensinogen precursor protein by the actions of renin, angiotensin converting enzyme (ACE) and other peptidases. Ang II has a central role in cardiovascular homeostasis by regulating vasoconstriction, renal Na+ and water readsorption. In addition, Ang II induces cell growth and proliferation and has pro-inflammatory effects.

      Most of the physiological actions of Ang II are mediated by AT1; a member of the 7-transmembrane domain, G-protein coupled receptor (GPCR) superfamily. AT2 is also a GPCR, and is largely believed to have counter-regulatory roles to the ones exerted through the AT1 receptor. Hence, binding of Ang II to the AT2 receptor will result in growth arrest and apoptosis, vasodilatation and hypotension.

Shipping and Ordering information