Neuropeptide Y Receptor Antibody Explorer Kit

A Screening Package of Neuropeptide Y Receptor Antibodies Economically Priced
  • Lyophilized Powder
  • Antigen Incl.
Cat #: AK-540
Sizes: 8 Vials
Last update: 24/04/2019

Alomone Labs is pleased to offer the Neuropeptide Y Receptor Antibody Explorer Kit (#AK-540). The Explorer Kit contains neuropeptide Y receptor antibodies, ideal for screening purposes.

For research purposes only, not for human use
Compounds
Product NameCat #Size
Anti-NPY1R Antibody
ANR-021 1 x 50 µl
Anti-NPY2R Antibody
ANR-022 1 x 50 µl
Anti-NPY4R Antibody
ANR-024 1 x 50 µl
Anti-NPY5R Antibody
ANR-025 1 x 50 µl
Scientific Background
    • Neuropeptide Y (NPY) is a 36-amino acid peptide neurotransmitter in the central (CNS) and peripheral nervous systems.1 It belongs to the NPY family, together with the peptide YY (PYY) and the pancreatic polypeptide (PP). NPY is involved in regulation of a broad range of homeostatic functions such as eating behavior, hypertension, and reproduction.2

      NPY exerts its effects via five receptor subtypes known as the neuropeptide Y receptors (NPYR): Y1 (NPY1R), Y2 (NPY2R), Y4 (NPY4R), Y5 (NPY5R) and Y6 (NPY6R).2 Four of these, Y1, Y2, Y4, and Y5, are expressed in humans.

      The NPY receptors belong to the G protein-coupled receptor superfamily whose members share a common structure of seven putative transmembrane domains, an extracellular amino terminus, and a cytoplasmic carboxyl terminus.

      Activation of these receptors by NPY produces effects on [Ca2+]i, adenylate cyclase, and a number of ion channels.Based on the high frequency and density of NPY receptors in steroid hormone-producing tumors, the NPY receptors might be of potential use in tumor management.2

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