KV2 Channel Blocker Explorer Kit

A Screening Package of KV2 Channel Blockers Economically Priced
  • Lyophilized Powder
  • Bioassay Tested
Cat #: EK-220
Last update: 24/01/2020

Alomone Labs is pleased to offer the KV2 Channel Blocker Explorer Kit (#EK-220). The Explorer Kit contains KV2 channel blockers, ideal for screening purposes.

For research purposes only, not for human use


Product NameCat #Size
Citalopram hydrobromide
C-185 1 x 25 mg
STG-200 1 x 0.1 mg
STJ-200 1 x 50 µg
STJ-300 1 x 50 µg
STP-400 1 x 50 µg
STS-350 1 x 50 µg

Scientific Background

    • KV2.2 is a member of the voltage-gated K+ channel superfamily. Together with the closely related KV2.1 protein they form the KV2 subfamily also known as Shab1-3.

      As with all KV channels, KV2.2 possesses the signature structure of the voltage-dependent K+ channels: six membrane-spanning domains with intracellular N and C termini. The functional KV channel is a tetramer that can either be a homotetramer or a heteromer of KV2.2 and KV2.1 subunits1-3.

      The pharmacology of the KV2.2 channel is somewhat limited. The channel is blocked by the classical K+ channel blockers tetraethylammonium (TEA) and 4-aminopyridine (4-AP). More recently, the small peptide toxin Stromatoxin-1 has been found to be a potent and more specific inhibitor of the KV2 subfamily4.

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