Overview
Cat #: AK-220
Size: 36 Vials
Form: Lyophilized
Alomone Labs is pleased to offer the Shaker (KV)-Related Channel Antibody Explorer Kit (#AK-220). This Explorer Kit includes antibodies targeted against KV2, KV3 and KV4 channels along with their respective peptide control antigen. An ideal tool for screening purposes.
For research purposes only, not for human use
Compounds
Scientific Background
Scientific Background K+ selective channels are some of the most widespread ion trafficking molecules in living organisms, with more than 70 genes encoding different K+ channels in humans. KV channels fall into one of the two classical categories of delayed rectifier (DR) and A-type. Delayed rectifier was the original name attributed to voltage-dependent K+ channels due to their delayed activation in squid giant axons. A-type channels are low voltage-activated, fast inactivating (therefore, transient) K+ channels. Specific KV toxins are often used to dissect the particular contribution of different subunits to native currents.
