Name: P2X7 Receptor Antagonist Explorer Kit
Brand: Alomone Labs
SKU: EK-410

Overview

Cat #: EK-410

Size: 13 Vials

Form: Lyophilized

P2X7 Receptor Antagonist Explorer Kit (#EK-410) contains P2X7 receptor antagonists, ideal for screening purposes.

For research purposes only, not for human use

Compounds

Product Name	Cat #	Size
A-740003	A-420	1 x 10 mg
A-804598	A-415	1 x 5 mg
A-839977	A-470	1 x 5 mg
AACBA hydrochloride	A-410	1 x 5 mg
AZ 10606120 dihydrochloride	A-405	1 x 5 mg
AZ11645373	A-395	1 x 5 mg
AZD-9056 hydrochloride	A-425	1 x 1 mg
CAY10593 (VU0155069)	C-385	1 x 5 mg
GW 791343 hydrochloride	G-115	1 x 5 mg
JNJ-47965567	J-115	1 x 5 mg
JNJ-54166060	J-125	1 x 5 mg
KN-62	K-120	1 x 1 mg
ZINC58368839	Z-135	1 x 5 mg

Scientific Background

Scientific Background P2X7 receptor is a member of the ionotropic P2X receptor family, activated by ATP. P2X7 receptor is found in cells of the immune system, particularly antigen presenting cells, and microglia. P2X7 receptor mediates the release of proinflamatory cytokines, stimulation of transcription factors and may also have an important role in apoptosis^1-3.

References

Ding, Y. et al. (2000) J. Auton. Nerv. Syst. 81, 289.
Kim, M. et al. (2001) EMBO J. 20, 6347.
Chizh, B.A. and Illes, P. (2001) Pharmacol. Rev. 53, 553.

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Order Summary

P2X7 Receptor Antagonist Explorer Kit

Overview

Compounds

A-740003

A-804598

A-839977

AACBA hydrochloride

AZ 10606120 dihydrochloride

AZ11645373

AZD-9056 hydrochloride

CAY10593 (VU0155069)

GW 791343 hydrochloride

JNJ-47965567

JNJ-54166060

KN-62

ZINC58368839

Scientific Background

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