Overview
Cat #: AK-216
Size: 38 Vials
Form: Lyophilized
Alomone Labs is pleased to offer the Non-L-Type CaV Channel Antibody Explorer Kit (#AK-216). The Explorer Kit contains non-L-type CaV channel antibodies, ideal for screening purposes.
For research purposes only, not for human use
Compounds
Scientific Background
Scientific Background Voltage-dependent Ca2+ channels (Cav) form an important route for Ca2+ entry into cells, upon deviations from the cells’ resting membrane potential. There are ten Cav α1 subunit genes, divided into three subfamilies on both a functional and sequence homology basis. The Cav1 subfamily includes four genes which encode the L-type channels, the Cav3 subfamily includes three genes encoding the T-type channels and the Cav2 subfamily consists of three isoforms encoding P/Q- , N- and R-type channels, with all three contributing to neurotransmitter release in neurons.
References
- Catterall, W.A. et al. (2003) Pharmacol. Rev. 55, 579.
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Shipping and Ordering information
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