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T-Type CaV Channel Blocker Explorer Kit

A Screening Package of T-Type CaV Channel Blockers Economically Priced
  • Lyophilized Powder
  • Bioassay Tested
  • Shipped at Room Temp.
  • 100% Net Peptide
Cat #: EK-111
Sizes: 19 Vials
Last update: 16/10/2018

Alomone Labs is pleased to offer the T-Type CaV Channel Blocker Explorer Kit (#EK-111). The Explorer Kit contains many classical T-type CaV channel blockers, ideal for screening purposes.

For research purposes only, not for human use
Compounds
Product Name Cat # Size
Amlodipine
 		A-110 1 x 250 mg
Amlodipine besylate
 		A-120 1 x 10 mg
L-Ascorbic acid
 		L-140 1 x 10 g
Benidipine hydrochloride
 		B-120 1 x 5 mg
Flunarizine dihydrochloride
 		F-110 1 x 1 g
GTx1-15
 		STT-300 1 x 50 µg
Loperamide hydrochloride
 		L-100 1 x 5 g
Mibefradil dihydrochloride hydrate
 		M-150 1 x 1 mg
ML 218
 		M-165 1 x 5 mg
ML 218 hydrochloride
 		M-166 1 x 5 mg
Nicardipine HCl
 		N-125 1 x 1 g
NNC 55-0396 dihydrochloride
 		N-205 1 x 5 mg
NNC 55-0396 dihydrochloride hydrate
 		N-206 1 x 5 mg
Penfluridol
 		P-135 1 x 25 mg
ProTx-I
 		STP-400 1 x 50 µg
ProTx-II
 		STP-100 1 x 50 µg
SKF 96365 hydrochloride
 		S-175 1 x 5 mg
TTA-A2
 		T-140 1 x 5 mg
TTA-P2
 		T-155 1 x 5 mg
References
Scientific Background

Voltage-dependent Ca2+ channels (CaV) form an important route for Ca2+ entry into cells upon deviations from the cell's resting membrane potential.  There are ten CaV α1 subunit genes, divided into three subfamilies on both a functional and sequence homology basis. The CaV1 subfamily includes four genes which encode the L-type channels, the CaV3 subfamily includes three genes encoding the T-type channels and the CaV2 subfamily consists of three isoforms encoding P/Q- , N- and R-type channels, with all three contributing to neurotransmitter release in neurons.
References
  1. Catterall, W.A. et al. (2003) Pharmacol. Rev. 55, 579.
Related Products
Related products
  1. L-Type CaV Channel Antibody Explorer Kit (#AK-215)
  2. Non-L-Type CaV Channel Antibody Explorer Kit (#AK-216)
  3. L-Type CaV Channel Blocker Explorer Kit (#EK-103)
  4. CaV2 Channel Blocker Explorer Kit (#EK-110)