Overview
Alomone Labs is pleased to offer the T-Type CaV Channel Blocker Explorer Kit (#EK-111). The Explorer Kit contains many classical T-type CaV channel blockers, ideal for screening purposes.
Compounds
Compounds
Product Name | Cat # | Size |
---|---|---|
Amlodipine |
A-110 | 1 x 250 mg |
Amlodipine besylate |
A-120 | 1 x 10 mg |
L-Ascorbic acid |
L-140 | 1 x 10 g |
Benidipine hydrochloride |
B-120 | 1 x 5 mg |
Flunarizine dihydrochloride |
F-110 | 1 x 1 g |
GTx1-15 |
STT-300 | 1 x 50 µg |
Kurtoxin |
STK-800 | 1 x 25 µg |
Loperamide hydrochloride |
L-100 | 1 x 5 g |
Mibefradil dihydrochloride hydrate |
M-150 | 1 x 1 mg |
ML 218 |
M-165 | 1 x 5 mg |
ML 218 hydrochloride |
M-166 | 1 x 5 mg |
Nicardipine HCl |
N-125 | 1 x 1 g |
NNC 55-0396 dihydrochloride |
N-205 | 1 x 5 mg |
NNC 55-0396 dihydrochloride hydrate |
N-206 | 1 x 5 mg |
Penfluridol |
P-135 | 1 x 25 mg |
ProTx-I |
STP-400 | 1 x 50 µg |
ProTx-II |
STP-100 | 1 x 50 µg |
SKF 96365 hydrochloride |
S-175 | 1 x 5 mg |
TTA-A2 |
T-140 | 1 x 5 mg |
TTA-P2 |
T-155 | 1 x 5 mg |
Scientific Background
Scientific Background
Voltage-dependent Ca2+ channels (CaV) form an important route for Ca2+ entry into cells upon deviations from the cell's resting membrane potential. There are ten CaV α1 subunit genes, divided into three subfamilies on both a functional and sequence homology basis. The CaV1 subfamily includes four genes which encode the L-type channels, the CaV3 subfamily includes three genes encoding the T-type channels and the CaV2 subfamily consists of three isoforms encoding P/Q- , N- and R-type channels, with all three contributing to neurotransmitter release in neurons.
- Catterall, W.A. et al. (2003) Pharmacol. Rev. 55, 579.
Related Products
Resources
Need Help With This Product?
Our reagent specialists are here to help you find the best product for your application. Please call or email us and we will be happy to help you find the right product for the job.
Call us at
+972 2587 2202 or Email Us