This product has recently been released.
This product is freeze dried. All water molecules have been removed.
The activity of this product has been verified and approved by our professional team.
This lyophilized product is shipped at room temperature. Please see its certificate of analysis for further storage instructions.
U 93631 is a synthetic compound that acts as an antagonist of the gamma-aminobutyric acid type A GABA(A) receptors and of 5-hydroxytryptamine type 3A (5-HT3A) receptors, displaying an IC50 of 50 µM for the serotonin receptor4. The compound accelerates the decay of GABA induced currents through an allosteric manner. The properties of U 93631 are shown to be analogous to those of picrotoxin and both share overlapping binding domains1,2.
GABA(A) receptors and 5-HT3 (serotonin-gated) receptor channels are members of the Cys-loop superfamily of ligand-gated ion channels. These receptors are expressed throughout the central and peripheral nervous systems and mediate a variety of important physiological functions. GABA(A) receptors mediate the actions of GABA, a major inhibitory neurotransmitter. 5-HT3 receptors mediate those of serotonin3.
Alomone Labs is pleased to offer U 93631 (#U-120).
- Anti-GABA(A) α1 Receptor (extracellular) (#AGA-001)
- Anti-GABA(A) α1 Receptor (extracellular)-ATTO-488 (#AGA-001-AG)
- Anti-GABA(A) α2 Receptor (#AGA-002)
- GABA(A) Receptor Antibody Explorer Kit (#AK-229)
- Anti-5-Hydroxytryptamine Receptor 3A (#ASR-031)
- α-Asarone (#A-260)
- (+)-Bicuculline (#B-135)
- Bilobalide (#B-145)
- GABA(A) Receptor Modulator Explorer Kit (#EK-360)
- Picrotoxin (#P-325)
- CGS 20625 (#C-390)
- Etbicyphat (#E-175)
- GABA(A)-compound 1b (#CMG-004)