This product is freeze dried. All water molecules have been removed.
The activity of this product has been verified and approved by our professional team.
- Luna-Ramirez K. et al. (2014) Mol. Pharmacol. 86, 28.
Urotoxin is a peptide toxin originally isolated from Urodacus yaschenkoi Australian Scorpion venom. Urotoxin is an extremely potent blocker of human voltage-gated potassium channel KV1.2 channels with IC50 values of 160 pM. However, it also displays activity towards KV1.1, KV1.3 and KCa3.1 with IC50 values of 253 nM, 91 nM and 70 nM respectively1.
Potassium channels are membrane proteins found in excitable and nonexcitable cells. KV1.2 channel plays an important role in the maintenance of resting membrane potential and the regulation of the cellular excitability of neurons1,2.
Urotoxin (#STU-200) is a highly pure, synthetic, and biologically active peptide toxin.