Mouse BV-2 Microglia Antibody Explorer Kit

A Screening Package of Mouse BV-2 Microglia Antibodies Economically Priced
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Cat #: AK-675

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Last update: 10/04/2020

Mouse BV-2 Microglia Antibody Explorer Kit (#AK-675) is a budget friendly screening package.

For research purposes only, not for human use



Scientific Background

Scientific Background
    • Microglia are the resident immune cells of the central nervous system that mediate an array of critical functions like neuronal development and connectivity as well as protecting their environment from unwelcome invaders1,4. On the other hand, microglia are also implicated in a variety of inflammatory and neurological disorders such as Alzheimer's disease, epilepsy, and schizophrenia3.

      More recently, interest in microglia has resurfaced after numerous studies found them important in regulating neuronal connectivity2. These studies also demonstrated that microglia cells could form synaptic connections between neurons during embryonic stage or during synaptic plasticity processes to enhance neuronal function2.

      BV-2 cell line originating from mouse is a common cell model used to study microglia.

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