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Lyophilized Powder Lyophilized PowderThis product is freeze dried. All water molecules have been removed.
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Antigen Incl. Control Antigen IncludedThis antibody is shipped with its antigen FREE of charge!
Last update: 24/01/2020
Alomone Labs is pleased to offer the Store-Operated Ca2+ Channel Antibody Explorer Kit (#AK-209). This Explorer Kit includes antibodies targeted against CRAC channels along with their respective peptide control antigen (excludes mouse monoclonal antibodies). An ideal tool for screening purposes.
For research purposes only, not for human use
Compounds
Compounds
| Product Name | Cat # | Size |
|---|---|---|
Anti-Orai1 (extracellular) Antibody | ACC-062 | 1 x 50 µl |
Anti-Human Orai1 (extracellular) Antibody | ACC-060 | 1 x 50 µl |
Mouse Anti-Human Orai1 (extracellular) Antibody | ALM-025 | 1 x 25 µg |
Anti-Orai2 Antibody | ACC-061 | 1 x 50 µl |
Anti-Orai3 Antibody | ACC-065 | 1 x 50 µl |
Anti-TMEM66 Antibody | ACC-067 | 1 x 50 µl |
Anti-STIM1 (extracellular) Antibody | ACC-063 | 1 x 50 µl |
Anti-STIM2 Antibody | ACC-064 | 1 x 50 µl |
Anti-TRPC1 Antibody | ACC-010 | 1 x 50 µl |
Anti-TRPC1 (extracellular) Antibody | ACC-118 | 1 x 50 µl |
Note A mouse monoclonal antibody (#ALM-025) is included in this Explorer Kit. Please take into account when reacting with a secondary antibody.
Scientific Background
Scientific Background
- Changes in the cytoplasm free Ca2+ concentration [Ca2+]in regulate a large number of relevant physiological processes and have a major impact on cell development and function. The identification of STIM, the endoplasmic reticulum (ER) Ca2+ sensor, and Orai, a key subunit of the Ca2+ release-activated Ca2+ (CRAC) channel pore, have provided the tools to illuminate the mechanisms of CRAC channel regulation that play an important role in modulation of the free Ca2+ concentration in non-excitable cells. Store-operated Ca2+ entry (SOCE) is a common and ubiquitous mechanism for regulating Ca2+ influx into cells and is widely expressed in most tissues.
Shipping and Ordering information
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