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Store-Operated Ca2+ Channel Antibody Explorer Kit

A Screening Package of Store-Operated Ca2+ Channel Antibodies Economically Priced
  • Lyophilized Powder
  • Antigen Incl.
Cat #: AK-209
Sizes: 19 Vials
Last update: 23/04/2019

Alomone Labs is pleased to offer the Store-Operated Ca2+ Channel Antibody Explorer Kit (#AK-209). This Explorer Kit includes antibodies targeted against CRAC channels along with their respective peptide control antigen (excludes mouse monoclonal antibodies). An ideal tool for screening purposes.

For research purposes only, not for human use
Compounds
Product Name Cat # Size
Anti-Orai1 (extracellular) Antibody
 		ACC-062 1 x 50 µl
Anti-Human Orai1 (extracellular) Antibody
 		ACC-060 1 x 50 µl
Mouse Anti-Human Orai1 (extracellular) Antibody
 		ALM-025 1 x 25 µg
Anti-Orai2 Antibody
 		ACC-061 1 x 50 µl
Anti-Orai3 Antibody
 		ACC-065 1 x 50 µl
Anti-TMEM66 Antibody
 		ACC-067 1 x 50 µl
Anti-STIM1 (extracellular) Antibody
 		ACC-063 1 x 50 µl
Anti-STIM2 Antibody
 		ACC-064 1 x 50 µl
Anti-TRPC1 Antibody
 		ACC-010 1 x 50 µl
Anti-TRPC1 (extracellular) Antibody
 		ACC-118 1 x 50 µl
Note A mouse monoclonal antibody (#ALM-025) is included in this Explorer Kit. Please take into account when reacting with a secondary antibody.
Scientific Background
Scientific Background Changes in the cytoplasm free Ca2+ concentration [Ca2+]in regulate a large number of relevant physiological processes and have a major impact on cell development and function. The identification of STIM, the endoplasmic reticulum (ER) Ca2+ sensor, and Orai, a key subunit of the Ca2+ release-activated Ca2+ (CRAC) channel pore, have provided the tools to illuminate the mechanisms of CRAC channel regulation that play an important role in modulation of the free Ca2+ concentration in non-excitable cells. Store-operated Ca2+ entry (SOCE) is a common and ubiquitous mechanism for regulating Ca2+ influx into cells and is widely expressed in most tissues.
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