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Lyophilized Powder Lyophilized PowderThis product is freeze dried. All water molecules have been removed.
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Bioassay Tested Bioassay TestedThis antibody has undergone quality control and has been approved by our professional team.
Alomone Labs is pleased to offer the TRPV1 Channel Modulator Explorer Kit (#EK-114). The Explorer Kit contains TRPV1 blockers and activators, ideal for screening purposes.
Compounds
| Product Name | Cat # | Size |
|---|---|---|
A 784168 | A-345 | 1 x 5 mg |
A-889425 | A-195 | 1 x 1 mg |
AM 404 | A-190 | 1 x 5 mg |
Arvanil | A-335 | 1 x 10 mg |
BCTC | B-110 | 1 x 10 mg |
Capsaicin | C-125 | 1 x 50 mg |
Capsazepine | C-120 | 1 x 5 mg |
LASSBio-1135 | L-190 | 1 x 5 mg |
Nonivamide | N-220 | 1 x 250 mg |
OLDA | O-120 | 1 x 5 mg |
Olvanil | O-115 | 1 x 5 mg |
Palvanil | P-205 | 1 x 5 mg |
SB-366791 | S-180 | 1 x 10 mg |
SB-705498 | S-160 | 1 x 5 mg |
Scientific Background
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TRPV1 (also named VR1, capsaicin receptor and vanilloid receptor) is a member of the transient receptor potential (TRP) channel family, which includes TRPC, TRPM, TRPA, TRPP, TRPML and the TRPV subfamilies. The TRPV subfamily consists of six members named, TRPV1-6. The TRPV1 channel is a vanilloid gated, nonselective cation channel.
TRPV1 has many activators among them heat, protons, vanilloids like Capsaicin, Resiniferatoxin (RTX), and lipids. This channel is associated with tissue injury and inflammation1,2.
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- Ross, R.A. et al. (2003) Br. J. Pharmacol. 140, 790.
- Tominaga, M. et al. (1998) Neuron 21, 531.
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