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Connexin Antibody Explorer Kit

A Screening Package of Connexin Antibodies for Economically Priced
  • Lyophilized Powder
  • Antigen Incl.
Cat #: AK-420
Sizes: 18 Vials
Last update: 24/04/2019

Alomone Labs is pleased to offer the Connexin Antibody Explorer Kit (#AK-420). This Explorer Kit includes connexin antibodies, ideal for screening purposes.

For research purposes only, not for human use
Compounds
Product Name Cat # Size
Anti-Connexin-26 (GJB2) Antibody
 		ACC-212 1 x 50 µl
Anti-Connexin-29 (extracellular) Antibody
 		ACC-223 1 x 50 µl
Anti-Connexin-31 (GJB3) Antibody
 		ACC-213 1 x 50 µl
Anti-Connexin-32 Antibody
 		ACC-211 1 x 50 µl
Anti-Connexin-36 Antibody
 		ACC-209 1 x 50 µl
Anti-Connexin-37 Antibody
 		ACC-204 1 x 50 µl
Anti-Connexin-40 (GJA5) Antibody
 		ACC-205 1 x 50 µl
Anti-Connexin-43 Antibody
 		ACC-201 1 x 50 µl
Anti-Connexin-45 (GJC1) Antibody
 		ACC-207 1 x 50 µl
Scientific Background
    • Connexins (Cx) are integral membrane proteins consisting of four transmembrane domains, two extracellular loops, one intracellular loop and intracellular N- and C-termini. The 21 members belonging to this family form homomeric or heteromeric hexamers generally termed connexons or hemi-channels. In turn, these hemi-channels further assemble in a head-to-head manner, thus forming gap junction channels1,2. Connexins are ubiquitously expressed and their activity is regulated at the expression level and by post-translational modifications1. For example, Connexin-43 (Cx43) protein level is regulated by its turnover rate and by phosphorylation of various residues which ultimately determines its activity rate1.
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