Name: Connexin Antibody Explorer Kit
Brand: Alomone Labs
SKU: AK-420

Overview

Cat #: AK-420

Size: 18 Vials

Form: Lyophilized

Alomone Labs is pleased to offer the Connexin Antibody Explorer Kit (#AK-420). This Explorer Kit includes connexin antibodies, ideal for screening purposes.

For research purposes only, not for human use

Compounds

Product Name	Cat #	Size
Anti-Connexin-26 (GJB2) Antibody	ACC-212	1 x 50 µl
Connexin-26/GJB2 Blocking Peptide	BLP-CC212	1 x 40 µg
Anti-Connexin-29 (extracellular) Antibody	ACC-223	1 x 50 µl
Connexin-29 (extracellular) Blocking Peptide	BLP-CC223	1 x 40 µg
Anti-Connexin-31 (GJB3) Antibody	ACC-213	1 x 50 µl
Connexin-31/GJB3 Blocking Peptide	BLP-CC213	1 x 40 µg
Anti-Connexin-32 Antibody	ACC-211	1 x 50 µl
Connexin-32 Blocking Peptide	BLP-CC211	1 x 40 µg
Anti-Connexin-36 Antibody	ACC-209	1 x 50 µl
Connexin-36 Blocking Peptide	BLP-CC209	1 x 40 µg
Anti-Connexin-37 Antibody	ACC-204	1 x 50 µl
Connexin-37 Blocking Peptide	BLP-CC204	1 x 40 µg
Anti-Connexin-40 (GJA5) Antibody	ACC-205	1 x 50 µl
Connexin-40/GJA5 Blocking Peptide	BLP-CC205	1 x 40 µg
Anti-Connexin-43 Antibody	ACC-201	1 x 50 µl
Connexin-43 Blocking Peptide	BLP-CC201	1 x 40 µg
Anti-Connexin-45 (GJC1) Antibody	ACC-207	1 x 50 µl
Connexin-45/GJC1 Blocking Peptide	BLP-CC207	1 x 40 µg

Scientific Background

Scientific Background Connexins (Cx) are integral membrane proteins consisting of four transmembrane domains, two extracellular loops, one intracellular loop and intracellular N- and C-termini. The 21 members belonging to this family form homomeric or heteromeric hexamers generally termed connexons or hemi-channels. In turn, these hemi-channels further assemble in a head-to-head manner, thus forming gap junction channels^1,2. Connexins are ubiquitously expressed and their activity is regulated at the expression level and by post-translational modifications¹. For example, Connexin-43 (Cx43) protein level is regulated by its turnover rate and by phosphorylation of various residues which ultimately determines its activity rate¹.

References

Goodenough, D.A. and Paul, D.L. (2011) Cold Spring Harb. Persp. Biol. 2009, 1.
Nakagawa, S. et al. (2010) Curr. Opin. Struct. Biol. 20, 423.

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Shipping and Ordering information

Order Summary

Connexin Antibody Explorer Kit

Overview

Compounds

Anti-Connexin-26 (GJB2) Antibody

Connexin-26/GJB2 Blocking Peptide

Anti-Connexin-29 (extracellular) Antibody

Connexin-29 (extracellular) Blocking Peptide

Anti-Connexin-31 (GJB3) Antibody

Connexin-31/GJB3 Blocking Peptide

Anti-Connexin-32 Antibody

Connexin-32 Blocking Peptide

Anti-Connexin-36 Antibody

Connexin-36 Blocking Peptide

Anti-Connexin-37 Antibody

Connexin-37 Blocking Peptide

Anti-Connexin-40 (GJA5) Antibody

Connexin-40/GJA5 Blocking Peptide

Anti-Connexin-43 Antibody

Connexin-43 Blocking Peptide

Anti-Connexin-45 (GJC1) Antibody

Connexin-45/GJC1 Blocking Peptide

Scientific Background

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