Overview
Cat #: AK-420
Size: 18 Vials
Form: Lyophilized
Alomone Labs is pleased to offer the Connexin Antibody Explorer Kit (#AK-420). This Explorer Kit includes connexin antibodies, ideal for screening purposes.
For research purposes only, not for human use
Compounds
| Product Name | Cat # | Size |
|---|---|---|
Anti-Connexin-26 (GJB2) Antibody |
ACC-212 | 1 x 50 µl |
Connexin-26/GJB2 Blocking Peptide |
BLP-CC212 | 1 x 40 µg |
Anti-Connexin-29 (extracellular) Antibody |
ACC-223 | 1 x 50 µl |
Connexin-29 (extracellular) Blocking Peptide |
BLP-CC223 | 1 x 40 µg |
Anti-Connexin-31 (GJB3) Antibody |
ACC-213 | 1 x 50 µl |
Connexin-31/GJB3 Blocking Peptide |
BLP-CC213 | 1 x 40 µg |
Anti-Connexin-32 Antibody |
ACC-211 | 1 x 50 µl |
Connexin-32 Blocking Peptide |
BLP-CC211 | 1 x 40 µg |
Anti-Connexin-36 Antibody |
ACC-209 | 1 x 50 µl |
Connexin-36 Blocking Peptide |
BLP-CC209 | 1 x 40 µg |
Anti-Connexin-37 Antibody |
ACC-204 | 1 x 50 µl |
Connexin-37 Blocking Peptide |
BLP-CC204 | 1 x 40 µg |
Anti-Connexin-40 (GJA5) Antibody |
ACC-205 | 1 x 50 µl |
Connexin-40/GJA5 Blocking Peptide |
BLP-CC205 | 1 x 40 µg |
Anti-Connexin-43 Antibody |
ACC-201 | 1 x 50 µl |
Connexin-43 Blocking Peptide |
BLP-CC201 | 1 x 40 µg |
Anti-Connexin-45 (GJC1) Antibody |
ACC-207 | 1 x 50 µl |
Connexin-45/GJC1 Blocking Peptide |
BLP-CC207 | 1 x 40 µg |
Scientific Background
Scientific Background Connexins (Cx) are integral membrane proteins consisting of four transmembrane domains, two extracellular loops, one intracellular loop and intracellular N- and C-termini. The 21 members belonging to this family form homomeric or heteromeric hexamers generally termed connexons or hemi-channels. In turn, these hemi-channels further assemble in a head-to-head manner, thus forming gap junction channels1,2. Connexins are ubiquitously expressed and their activity is regulated at the expression level and by post-translational modifications1. For example, Connexin-43 (Cx43) protein level is regulated by its turnover rate and by phosphorylation of various residues which ultimately determines its activity rate1.
References
- Goodenough, D.A. and Paul, D.L. (2011) Cold Spring Harb. Persp. Biol. 2009, 1.
- Nakagawa, S. et al. (2010) Curr. Opin. Struct. Biol. 20, 423.
Related Products
Related Products
Shipping and Ordering information
Need Help With This Product?
Our reagent specialists are here to help you find the best product for your application. Please call or email us and we will be happy to help you find the right product for the job.
Call us at
+972 2587 2202 or Email Us
