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KCNQ (KV7) Channel Activator Explorer Kit

A Screening Package of KCNQ (KV7) Channel Activators Economically Priced
  • Lyophilized Powder
  • Bioassay Tested
Cat #: EK-225
Sizes: 9 Vials
Last update: 24/04/2019

Alomone Labs is pleased to offer the KCNQ (KV7) Channel Activator Explorer Kit (#EK-225). The Explorer Kit contains KCNQ channel activators, ideal for screening purposes.

For research purposes only, not for human use
Compounds
Product Name Cat # Size
Celecoxib
 		C-190 1 x 100 mg
Diclofenac
 		D-180 1 x 1 g
2,5-dimethylcelecoxib
 		D-150 1 x 5 mg
Flupirtine Maleate
 		F-150 1 x 5 mg
ICA-110381
 		I-160 1 x 5 mg
ICA-27243
 		I-130 1 x 5 mg
Meclofenamic acid
 		M-210 1 x 5 mg
NS-1643
 		N-115 1 x 10 mg
Retigabine dihydrochloride
 		R-101 1 x 10 mg
References

    • KCNQ genes encode members of the KV7 K+ channels. Structurally, the KCNQ family belongs to the six transmembrane domain category of K+ channels. Five members belong to this family (KCNQ1-KCNQ5) of which KCNQ2 to KCNQ5 are expressed in the nervous system1-3. KCNQ5 is also expressed in visceral smooth muscle4 and skeletal muscle5.

      These channels form subunits of the low threshold voltage gated K+ channel. KCNQ2 and KCNQ3 mostly form heteromers to form the M current. KCNQ5 is known to contribute to this current1.
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