KCNQ (KV7) Channel Modulator Explorer Kit

A Screening Package of KCNQ (KV7) Channel Modulators Economically Priced
  • Lyophilized Powder
  • Bioassay Tested
Cat #: EK-131
Sizes: 12 Vials
Last update: 24/04/2019

Alomone Labs is pleased to offer the KCNQ (KV7) Channel Modulator Explorer Kit (#EK-131). The Explorer Kit contains KCNQ channel blockers and activators, ideal for screening purposes.

For research purposes only, not for human use
Compounds
Product Name Cat # Size
2,5-dimethylcelecoxib
D-150 1 x 5 mg
Celecoxib
C-190 1 x 100 mg
Diclofenac
D-180 1 x 1 g
Flupirtine Maleate
F-150 1 x 5 mg
ICA-27243
I-130 1 x 5 mg
ICA-110381
I-160 1 x 5 mg
Linopirdine dihydrochloride
L-156 1 x 5 mg
Meclofenamic acid
M-210 1 x 5 mg
NS-1643
N-115 1 x 10 mg
QO-40
Q-265 1 x 5 mg
Retigabine dihydrochloride
R-101 1 x 10 mg
XE991 dihydrochloride
X-101 1 x 5 mg
References
    • KCNQ genes encode members of the KV7 K+ channels. Structurally, the KCNQ family belongs to the six transmembrane domain category of K+ channels. Five members belong to this family (KCNQ1-KCNQ5) of which KCNQ2 to KCNQ5 are expressed in the nervous system1-3. KCNQ5 is also expressed in visceral smooth muscle4 and skeletal muscle5.

      These channels form subunits of the low threshold voltage-gated K+ channel. KCNQ2 and KCNQ3 mostly form heteromers to form the M current. KCNQ5 is known to contribute to this current1.

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