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KCNQ (KV7) Channel Antibody Explorer Kit

A Screening Package of KCNQ Channel Antibodies Economically Priced
  • Lyophilized Powder
  • Antigen Incl.
Cat #: AK-221
Sizes: 22 Vials
Last update: 15/07/2019

Alomone Labs is pleased to offer the KCNQ (KV7) Channel Antibody Explorer Kit (#AK-221). This Explorer Kit includes antibodies targeted against KCNQ channels and subunits along with their respective peptide control antigen. An ideal tool for screening purposes.

For research purposes only, not for human use
Compounds
Product Name Cat # Size
Anti-KCNQ1 Antibody
 		APC-022 1 x 50 µl
Guinea pig Anti-KCNQ1 Antibody
 		AGP-050 1 x 50 µl
Anti-KCNQ1 (extracellular) Antibody
 		APC-168 1 x 50 µl
Anti-KCNQ2 Antibody
 		APC-050 1 x 50 µl
Anti-KCNQ3 Antibody
 		APC-051 1 x 50 µl
Anti-KCNQ4 Antibody
 		APC-164 1 x 50 µl
Anti-KCNQ5 Antibody
 		APC-155 1 x 50 µl
Anti-KCNE1 (IsK) Antibody
 		APC-163 1 x 50 µl
Anti-KCNE2 (MiRP1) Antibody
 		APC-054 1 x 50 µl
Anti-KCNE3 (MiRP2) Antibody
 		APC-118 1 x 50 µl
Anti-KCNE4 (MiRP3) Antibody
 		APC-129 1 x 50 µl
Scientific Background

    • The KCNQ family of voltage-gated K+ channels includes 5 known members: KCNQ1 to KCNQ5. Structurally, the KCNQ family belongs to the six transmembrane domain category of K+ channels. KCNQ family members can form either homomultimeric or heteromultimeric channels with different functional consequences. For example, KCNQ2 and KCNQ3 heteromultimers give rise to a much larger channel current than when either protein is expressed alone, probably due to enhanced plasma membrane expression of the combined channel. Indeed, KCNQ2/KCNQ3 heteromultimers are believed to be the molecular correlates of the so-called M current. This current is a K+ neuronal current that is strongly inhibited by the activation of the M1 subtype of the muscarinic acetylcholine receptor. KCNQ5 is also expressed in visceral smooth muscle4 and skeletal muscle.
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