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Lyophilized Powder Lyophilized PowderThis product is freeze dried. All water molecules have been removed.
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Bioassay Tested Bioassay TestedThis antibody has undergone quality control and has been approved by our professional team.
Alomone Labs is pleased to offer the ASIC Channel Modulator Explorer Kit (#EK-113). The Explorer Kit contains ASIC blockers and activators, ideal for screening purposes.
Compounds
| Product Name | Cat # | Size |
|---|---|---|
alpha/beta MitTx | M-100 | 1 x 5 µg |
Amiloride hydrochloride | A-140 | 1 x 1 g |
APETx2 | STA-160 | 1 x 0.1 mg |
Cono AIVGRPRF-amide | STC-174 | 1 x 0.5 mg |
Cono RPRF-amide | STC-170 | 1 x 0.5 mg |
Cono VGRPRF-amide | STC-172 | 1 x 0.5 mg |
GMQ | G-130 | 1 x 5 mg |
GMQ hydrochloride | G-165 | 1 x 5 mg |
Hm3a Toxin | STH-250 | 1 x 50 µg |
Mambalgin-3 | STM-500 | 1 x 50 µg |
Psalmotoxin-1 | STP-200 | 1 x 50 µg |
Scientific Background
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Acid-sensing ion channels (ASICs) are Na+ channels activated by external protons. The ASIC family includes four members: ASIC1, ASIC2, ASIC3 and ASIC4. The ASIC family is in fact part of a large channel superfamily known as degenerin/epithelial Na+ channels (DEG/ENaC) and share the same basic characteristics: two transmembrane spanning domains, a large extracellular domain and short intracellular N- and C- termini.
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