Overview
Alomone Labs is pleased to offer the KCa Channel Opener Explorer Kit (#EK-201). The Explorer Kit contains KCa openers, ideal for screening purposes.
Compounds
| Product Name | Cat # | Size |
|---|---|---|
CyPPA |
C-110 | 1 x 5 mg |
1-EBIO |
E-150 | 1 x 10 mg |
Isopimaric Acid |
I-370 | 1 x 1 mg |
NS-11021 |
N-335 | 1 x 5 mg |
NS-1619 |
N-105 | 1 x 5 mg |
NS19504 |
N-235 | 1 x 5 mg |
NS-309 |
N-180 | 1 x 5 mg |
Pimaric Acid |
P-270 | 1 x 1 mg |
SKA-31 |
S-120 | 1 x 5 mg |
SKA-121 |
S-245 | 1 x 5 mg |
Tanshinone II-A sodium sulfonate |
T-165 | 1 x 5 mg |
Scientific Background
Ca2+-dependent K+ (KCa) channels are divided into two main groups based on their biophysical properties and gene homology. KCa were first divided according to their single channel conductance, which represents the speed by which the K+ passes through the open channel. The first group consists of small and intermediate conductance channels (SK and IK respectively, the KCNN gene family). The second group is comprised of large/big conductance channels (called BKCa or maxiK, encoded by the slo or KCNMA1 gene)1.
- Coetzee, W.A. et al. (1999) Annals N.Y. Aced. Sci. 868, 233.
Related Products
Pharmacological tools
- KCa Channel Blocker Explorer Kit (#EK-101)
- Anti-sloβ1 (KCNMB1) Antibody (#APC-036)
- Anti-sloβ2 (KCNMB2) Antibody (#APC-034)
- Anti-sloβ4 (KCNMB4) Antibody (#APC-061)
- Anti-KCNT1 (Slack) Antibody (#APC-124)
- Anti-KCNT2 (Slick) Antibody (#APC-126)
- BKCa Channel Antibody Explorer Kit (#AK-217)
- SK (Non-BKCa) Channel Antibody Explorer Kit (#AK-218)
- KCa1.1 Channel Modulator Explorer Kit (#EK-132)
- KCa2-Related Channel Modulator Explorer Kit (#EK-122)
- KCNN4 (KCa3.1, SK4) Channel Modulator Explorer Kit (#EK-133)
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