Overview
Alomone Labs is pleased to offer the Kir Channel Antibody Explorer Kit (#AK-200). This Explorer Kit includes antibodies targeted against Kir channels along with their respective peptide control antigen (where applicable). An ideal tool for screening purposes.
Compounds
Scientific Background
Kir1.1 (ROMK1) was the first member of the family of inward rectifying K+ channels to be cloned1. The family includes 15 members that are structurally and functionally different from the voltage-dependent K+ channels.
The family’s topology consists of two transmembrane domains that flank a single and highly conserved pore region with intracellular N- and C-termini. As is the case for the voltage-dependent K+ channels the functional unit for the Kir channels is composed of four subunits that can assembly as either homo- or heterotetramers.
Kir channels are characterized by a K+ efflux that is limited by depolarizing membrane potentials thus making them essential for controlling resting membrane potential and K+ homeostasis2.
- Ho, K. et al. (1993) Nature 362, 31.
- Wang, W.H. (2006) Am. J. Physiol. Renal Physiol. 290, F14.
Related Products
- Anti-Kir2.1/KCNJ2 (extracellular) Antibody (#APC-159)
- Guinea pig Anti-Kir2.1/KCNJ2 Antibody (#APC-026-GP (formerly AGP-044))
- Guinea pig Anti-GIRK2 (Kir3.2) Antibody (#APC-006-GP (formerly AGP-013))
- GIRK2 (Kir3.2) Channel Antibody and Membrane Fractions Kit (#LK-102)
- Anti-Kir4.1 (KCNJ10)-ATTO Fluor-488 Antibody (#APC-035-AG)
- Anti-Kir7.1 (extracellular)-ATTO Fluor-488 Antibody (#APC-125-AG)
- δ-Dendrotoxin (#D-380)
- Lq2 (#RTL-550)
- Tertiapin (#STT-250)
- Tertiapin-Q (#STT-170)
- Tertiapin-Q-ATTO Fluor-488 (#STT-170-AG)
- VU0529331 (#V-155)
- GIRK (Kir3) Channel Antibody Explorer Kit (#AK-227)
- Cardiac Kir Channel Antibody Explorer Kit (#AK-330)
- pH-Sensitive Kir Channel Antibody Explorer Kit (#AK-460)
- K+ Channel Antibodies for Pain Research Explorer Kit (#AK-390)
- Kir Channel Blocker Explorer Kit (#EK-112)
- K+ Channel Blockers for Pain Research Explorer Kit (#EK-390)
Need Help With This Product?
Our reagent specialists are here to help you find the best product for your application. Please call or email us and we will be happy to help you find the right product for the job.
Call us at
+972 2587 2202 or Email Us