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Kir Channel Antibody Explorer Kit

A Screening Package of Kir Channel Antibodies Economically Priced
  • Lyophilized Powder
  • Antigen Incl.
Cat #: AK-200
Sizes: 35 Vials
Last update: 23/04/2019

Alomone Labs is pleased to offer the Kir Channel Antibody Explorer Kit (#AK-200). This Explorer Kit includes antibodies targeted against Kir channels along with their respective peptide control antigen (where applicable). An ideal tool for screening purposes.

For research purposes only, not for human use
Compounds
Product Name Cat # Size
Anti-KCNJ1 (Kir1.1) Antibody
 		APC-001 1 x 50 µl
Anti-Kir2.1 (KCNJ2) Antibody
 		APC-026 1 x 50 µl
Anti-Kir2.2 (KCNJ12) Antibody
 		APC-042 1 x 50 µl
Anti-Kir2.3 (KCNJ4) Antibody
 		APC-032 1 x 50 µl
Anti-GIRK1 (Kir3.1) Antibody
 		APC-005 1 x 50 µl
Mouse Anti-GIRK1 (Kir3.1) (extracellular) Antibody
 		ALM-031 1 x 25 µg
Anti-GIRK2 (Kir3.2) Antibody
 		APC-006 1 x 50 µl
Anti-GIRK3 (Kir3.3) Antibody
 		APC-038 1 x 50 µl
Anti-KCNJ5 (Kir3.4) Antibody
 		APC-027 1 x 50 µl
Anti-Kir4.1 (KCNJ10) Antibody
 		APC-035 1 x 50 µl
Guinea pig Anti-Kir4.1 (KCNJ10) Antibody
 		AGP-012 1 x 50 µl
Anti-Kir4.1 (KCNJ10) (extracellular) Antibody
 		APC-165 1 x 50 µl
Anti-KCNJ15 (Kir4.2) Antibody
 		APC-058 1 x 50 µl
Anti-Kir5.1 Antibody
 		APC-123 1 x 50 µl
Anti-Kir6.1 (KCNJ8) Antibody
 		APC-105 1 x 50 µl
Anti-Kir6.2 Antibody
 		APC-020 1 x 50 µl
Guinea pig Anti-Kir6.2 Antibody
 		AGP-067 1 x 50 µl
Anti-Kir7.1 (extracellular) Antibody
 		APC-125 1 x 50 µl
Note A mouse monoclonal antibody (#ALM-031) and guinea pig polyclonal antibodies (#AGP-012 & #AGP-067) are included in this Explorer Kit. Please take into account when reacting with a secondary antibody.
Scientific Background

    • Kir1.1 (ROMK1) was the first member of the family of inward rectifying K+ channels to be cloned1. The family includes 15 members that are structurally and functionally different from the voltage-dependent K+ channels.

      The family’s topology consists of two transmembrane domains that flank a single and highly conserved pore region with intracellular N- and C-termini. As is the case for the voltage-dependent K+ channels the functional unit for the Kir channels is composed of four subunits that can assembly as either homo- or heterotetramers.

      Kir channels are characterized by a K+ efflux that is limited by depolarizing membrane potentials thus making them essential for controlling resting membrane potential and K+ homeostasis2.
      1. Ho, K. et al. (1993) Nature 362, 31.
      2. Wang, W.H. (2006) Am. J. Physiol. Renal Physiol. 290, F14.
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